Shilpa Buch, PhD, is a professor and Vice Chair for Research in the Department of Pharmacology at University of Nebraska Medical Center. Her interests are in the area of HIV and substance abuse synergy in the progression of HIV-associated Neurocognitive Disorders (HAND) using the cell culture, rodent and macaque model systems. Her recent research focus is in the areas of miRNA regulation and exosome mediated cross talk of CNS cells. She has also a keen interest in other end organs such as the lung that are impacted with HIV and substance abuse. She has published extensively in peer-reviewed journals and is very passionate about mentoring junior faculty.
Prasun K. Datta, PhD, is an assistant professor in the Department of Neuroscience, Temple University School of Medicine, Philadelphia, USA. He received his PhD at the University of Calcutta, India. Dr. Datta is a recipient of an NIH/NIDA Career Development Award. The major research interests of the Datta lab are to elucidate the epigenetic mechanisms involved in the regulation of the glutamate transporter EAAT2 in the context of NeuroAIDS and the role of exosomes in the pathogenesis of NeuroAIDS.
Dolores Di Vizio, MD, PhD, is a pathologist and a molecular and cell biologist trained at Albert Einstein College of Medicine and Harvard Medical School. Dr. Di Vizio has been on faculty at Harvard University since 2007, and holds an academic appointment as associate professor at Cedars-Sinai Medical Center, and UCLA, Los Angeles. Her group studies the molecular mechanisms of progression to advanced disease in human tumors, with a particular emphasis on large oncosomes, extracellular vesicles released from fast migrating and metastatic amoeboid cancer cells. Her lab is currently profiling the large oncosomes by NGS and proteomics.
Uta Erdbrügger, MD, is an assistant professor of medicine in the Division of Nephrology at the University of Virginia Medical School. Dr. Erdbrügger earned her MD at the Free University in Berlin and completed post-graduate education at Berlin’s Humboldt University, Tulane University, and the University of North Carolina, Chapel Hill. Dr. Erdbrügger is interested in the role of circulating endothelial cells and endothelial microparticles in vascular and renal disorders. She also conducts research into the optimization of microparticle detection.
Steven M. Jay, PhD, is an assistant professor in the Fischell Department of Bioengineering at the University of Maryland. He received his Ph.D. from Yale University under the guidance of Dr. Mark Saltzman on the topics of protein delivery and cell-based therapies and completed postdoctoral work in molecular cardiology and protein engineering with Dr. Richard T. Lee at Brigham and Women’s Hospital and Dr. Linda Griffith at MIT. His research focuses broadly on development and delivery of biotherapeutics, with specific emphasis on both engineering extracellular vesicles for therapeutic application as well as developing novel extracellular vesicle biomanufacturing processes
Dimitrios Kapogiannis, MD, is a Clinical Investigator at the Laboratory of Neurosciences of the National Institute on Aging/NIH and Assistant Professor of Neurology at Johns Hopkins University. Dr. Kapogiannis is interested in exosomes as a source of predictive and diagnostic biomarkers for Alzheimer’s disease and other neurodegenerative diseases. In addition, he is the Principal Investigator of clinical trials in Alzheimer’s disease and is interested in validating exosomal markers as surrogate outcome measures.
Leonid Margolis, PhD, is a Senior Investigator and Chief of the Section of Intercellular Interactions at the National Institute of Child Health and Human Development, US National Institutes of Health. Dr. Margolis attended Lomonosov Moscow University and was was elected a member of the Russian Academy of Natural Sciences. Dr. Margolis joined NICHD in 1995. He developed a system of ex vivo human lymphoid tissues through which he and others investigated critical mechanisms of tissue pathogenesis of HIV-1 and other viruses under controlled laboratory conditions. His experimental tissue systems are widely used as platforms for the study of HIV pathogenesis and for testing antivirals. Dr. Margolis’s research is focused on inter-viral interactions in human tissues, the transmission of HIV-1 and herpesviruses, and the development of new antivirals, in particular microbicides.
Susmita Sahoo, PhD, is an assistant professor at Icahn School of Medicine at Mount Sinai, New York. She completed her education and training at the Indian Institute of Technology, Mumbai and at Northwestern University, Chicago. Her research program is focused on a comprehensive understanding of cellular, tissue and organ level micro-communication mechanisms that can contribute to novel therapeutic approaches in cardiovascular regenerative medicine. Specifically, she is interested in studying stem cell-derived exosomes and miRNAs in revival of cardiomyocytes, endothelium and the microenvironment in the ischemic heart.
Kenneth W. Witwer, PhD, (Chair) is an assistant professor in the Department of Molecular and Comparative Pathobiology at the Johns Hopkins University School of Medicine. He completed his education at Penn State University and Johns Hopkins. Dr. Witwer’s lab investigates biomarkers of HIV disease, cancers, and rare diseases and seeks to develop small RNA-based therapies. Dr. Witwer is also interested in the influence of diet on extracellular vesicles and small RNA profiles.